| Medication Class | Number of verified cases in literature as of 2019 | Medication |
| Vitamin A and derivatives | 84 | Vitamin A |
| Isotretinoin |
| Tretinoin |
| Tetracycline related antibiotics | 71 | Minocycline |
| Tetracycline |
| Doxycycline |
| Recombinant growth hormone | 24 | |
| Lithium | 17 | |
| Corticosteroids | 14 | |
| Sulfenazone | 9 | |
| First-generation fluroquinolone | 7 | Nalidixic acid |
| Cyclosporine | 7 | |
| GnRH/LHRH agonists | 6 | Leuprorelin |
| Amiodarone | 5 | |
| Progestin-only contraceptives | 4 | Norplant |
| Nexplanon |
| Second and third generation fluoroquinolones | 4 | Ciprofloxacin |
| Levofloxicin |
| Ofloxacin |
| Combined oral contraceptives | 3 | |
| Stanozolol | 1 | |
| Danazol | 1 | |
| Divalproic acid | 1 | |
| Sulfazalazine | 1 | |
| Ketoconazole | 1 | |
| Ustekinumab | 1 | |