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Vitreoretinal Precursors of Retinal Breaks

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  • Occurs in 8% (6-10%) slightly more than half are unilateral
  • 0.5-1% will get a retinal detachment
  • 20-30% of those with rhegmatogenous retinal detachments have lattice
  • Clinical appearance varies widely
    • most common is circumferential round, linear or ovoid areas of retinal thinning, often crossed by whitish lines that represent hyalinized retinal vessels
    • may also have superficial white/yellow flecks, patches of pigmentation, round or linear white patches or craters, small atrophic holes
  • Histologic appearance usually has one of the three:
    • localized thinning of inner retinal layers
    • vitreous liquefaction overlying thinned retina
    • vitreous condensation with exaggerated vitreoretinal attachments at the margins of the lesion
  • Associated with retinal tears, detachments, tractions which may be symptomatic or asymptomatic
  • Monitoring recommended if asymptomatic with a consideration for prophylactic treatment in a fellow eye of those with retinal detachment.

Byer's natural history study (423 eyes)

  • Subclinical retinal detachments 10/423 eyes
    • 1 disc diameter of subretinal fluid on all sides of the break
    • no extension posterior to the equator.
    • treatment needed in 1
  • Atrophic retinal holes 35%
  • Tractional retinal tears, asymptomatic 3/423 eyes
    • none treated and none progressed
  • Tractional retinal tears, symptomatic 5/423 eyes
    • all treated
  • Retinal detachment 3/423 eyes
    • two due to round retinal holes in lattice lesions
    • 1 from a symptomatic retinal tear
  • Recommendations from this study
    • Phakic eyes if asymptomatic should not a prophylactic treatment
    • Retinal detachment in the setting of vitreoretinal traction on lattice lesions containing round retinal holes is relatively common in the setting of significant myopia
  • May be responsible for 10% of clinical retinal detachments
  • associated with small horseshoe-shaped tears in absence of PVD
  • Chance of RD is 1/357
  • Prophylactic therapy is not recommended if present but otherwise normal