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Relative Potency of Opioids
| ANALGESIC | POTENCY RELATIVE TO MORPHINE | DURATION OF ACTION (HOURS) |
|---|---|---|
| Codeine Dihydrocodeine | 1/10 | 3-6 |
| Pethidine | 1/8 | 2-4 |
| Tapentadol | 1/3 | 4-6 |
| Hydrocodone | 2/3 | 4-8 |
| Oxycodone | 1.5 | 3-4 |
| Methadone | 5-10d | 8-12 |
| Hydromorphone | 4-5 | 4-5 |
| Buprenorphine (SL) | 80 | 6-8 |
| Buprenorphine(TD) | 100 | Formulation dependent (72-168) |
| Fentanyl (TD) | 100 | 72 |