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Noonan Syndrome

  • Highly variable but most have short stature, mild intellectual disability or developmental delay and
  • Characteristic faces
    • High forehead
    • depressed nasal bridge
    • low-set posteriorly rotated ears with fleshy helices
  • Refractive Errors: Myopia, hyperopia and astigmatism
  • Ptosis
  • Hypertelorism
  • Downslanting palpebral fissures
  • Epicanthal folds
  • Keratoconus
  • vivid blue or blue-green iris
  • Posterior embryotoxin
  • Cataract
  • Strabismus
  • Nystagmus
  • Optic nerve hypoplasia
  • Optic nerve coloboma