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Pediatric Intermediate Uveitis

Causes

* typically idiopathic * Juvenile Idiopathic Arthritis #1 * Intraocular lymphoma. (CBC with differential) * Lyme disease (antibody test) * toxocariasis (antibody test) * syphilis (antibody test) * HTLV-1 (antibody test) * bartonellosis (antibody test) * Multiple sclerosis (MRI brain, HLA-DR2 and HLA-DR15) * Sarcoidosis (ACE may be elevated normally, Chest Xray) * Necrotizing systemic vasculitis

* Collagen vascular diseases (HLA-B27)

  • Ankylosing Spondylitis
  • Inflammatory Bowel Diseases - (Ulcerative colitis, Crohn disease)
  • Psoriatic arthritis

Masqueraders

  • Endophthalmitis- suspect in the setting of recent surgery or intraocular injection, immunocompromised or parenteral nutrition or central line

Idiopathic

  • Pars planitis

Reference: AAO Pediatric Intermediate Uveitis