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EDTA for Corneal Chelation

a.k.a. disodium ethylenediaminetetraacetic acid, N2EDTA chelation agent for removing corneal calcium deposits

Preparation method

  1. 0.3 ml sterile water injected into a lavender top, 3.0 ml K2-EDTA BD Vacutainer CBC tube (each tube has 5.4 mg K2-EDTA)
  2. Swirl the liquid around to dissolve the droplets of liquid in the container
  3. Poor the contents into a second lavender top tube (will have to remove the tops of both tubes), repeat step 2
  4. Repeat step 3 for a total of 5 tubes
  5. results in 27 mg of K2-EDTA concentration of 9%, pH 5.8,
  6. Video example

References

  1. "Off-the-Shelf" K2-EDTA for Calcific Band Keratopahy. Lee et al. Cornea 2018;37(7):916-918
  2. Simplified, Readily Available Method for the Treatment of Band Keratopathy With Ethylenediaminetetraacetic Acid. Narvaez J. et al. Cornea 2021;40(10):1360-1362