Behçet's Disease

• Systemic vascular inflammatory disorder affecting skin, mucous membranes, eyes, lungs, GI tract and CNS. It is characterized by:
  • Mouth sores- aphthous ulcers usually first sign
  • Genital sores- (75%) small ulcers on scrotum or labia
  • Erythema Nodosum- painful red skin nodules
  • Also puss filled bumps in the skin
  • Arthritis
  • Ocular Inflammation (66%)
    • Conjunctivitis
    • Uveitis
      • Panuveitis with vasculitis
  • Rare associations
    • inflammation of the brain or spinal cord
    • blood clots, aneurism, GI vasculitis
  • Typically symptoms start in the 20's or 30's

Clinical Key Monograph