Show pageOld revisionsBacklinksBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== EDTA for Corneal Chelation ====== a.k.a. disodium ethylenediaminetetraacetic acid, N2EDTA chelation agent for removing corneal calcium deposits ====Preparation method 1 ==== - 0.3 ml sterile water injected into a lavender top, 3.0 ml K2-EDTA BD Vacutainer CBC tube (each tube has 5.4 mg K2-EDTA) - Swirl the liquid around to dissolve the coating in the container - Poor the contents into a second lavender top tube (will have to remove the tops of both tubes), repeat step 2 - Repeat step 3 for a total of 5 tubes - results in 65 mg/ml of K2-EDTA, pH 5.8, - [[http://links.lww.com/ICO/A633|Video example]] ====Peparation method 2 ==== - 0.3 ml sterile water injected into a 10 ml lavender top K2-EDTA BD Vacutaner tube (each tube has 18 mg K2-EDTA) - Swirl the liquid around to dissolve the coating of the container - results in about 35 mg/ml K2-EDTA ====Preparation method 3 ==== - 0.3 ml sterile water injected into a 10 ml lavender top K2-EDTA BD Vacutaner tube (each tube has 18 mg K2-EDTA) - Use a sterile cotton tip applicator to rub off all of the EDTA into the liquid - Use the cotton tip applicator to transfer the EDTA to the cornea - results in about 52 mg/ml K2-EDTA - [[https://cdn-links.lww.com/permalink/ico/b/ico_2020_11_17_narvaez_1_sdc1.mp4|Video Example]] ====References==== - [[https://1drv.ms/b/c/31d83ae8e55e0542/IQDv2isZOfgDQZX0Tp-gCQCJAWr5065taet4Q_9zVMKZTes?e=q60Y6X|"Off-the-Shelf" K2-EDTA for Calcific Band Keratopahy. Lee et al. Cornea 2018;37(7):916-918]] - [[https://1drv.ms/b/c/31d83ae8e55e0542/IQDLPKIpqwgARYqjxoi62JxkAQknFGQfWwO9n9HK23PO7T4?e=KnQpbO|Simplified, Readily Available Method for the Treatment of Band Keratopathy With Ethylenediaminetetraacetic Acid. Narvaez J. et al. Cornea 2021;40(10):1360-1362]]