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--- uveitis_classification [2016/08/08 22:50] – created Scott Larson
+++ uveitis_classification [2025/04/18 20:40] (current) – external edit 127.0.0.1
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+====== Classification of Uveitis ======
+**Standardization of Uveitis Nomenclature (SUN) working group scheme**
+===== Anatomic Classification =====
+^ Type          ^ Primary Site of Inflammation                       ^ Includes                                                                                                ^
+| Anterior      | Anterior Chamber                                   | Iritis, Iridocyclitis, Anterior cyclitis                                                                |
+| Intermediate  | Vitreous                                           | Pars Planitis, Posterior cyclitis, Hyalitis                                                             |
+| Posterior     | Retina or Choroid                                  | Focal, multifocal or diffuse choriditis; Chorioretinitis; Retinochoroiditis, Retinitis, Neuroretinitis  |
+| Panuveitis    | Anterior Chamber, Vitreous, and Retina or Choroid  |                                                                                                         |
+===== Grading of Anterior Chamber Cells =====
+^ Grade           ^ Cells in 1mm x 1 mm slit beam  ^
+| 0               | <1                             |
+| 0.5 + or Trace  | 1-5                            |
+| 1+              | 6-15                           |
+| 2+              | 16-25                          |
+| 3+              | 26-50                          |
+| 4+              | >50                            |
+===== Grading of Anterior Chamber Flare =====
+^ Grade  ^ Description                             ^
+| 0      | None                                    |
+| 1+     | Faint                                   |
+| 2+     | Moderate (iris and lens details clear)  |
+| 3+     | Marked (iris and lens details hazy)     |
+| 4+     | Intense (fibrin or plastic aqueous)     |
+===== Descriptors of Uveitis =====
+^ Category ^ Descriptor ^ Comment ^
+|Onset|Sudden| |
+|:::|Insidious| |
+|Duration|Limited|≤3 months duration|
+|:::|Persistent|≥3 months duration|
+|Course|Acute|Episode of sudden onset and limited duration|
+|:::|Recurrent|Repeat episodes separated by periods of inactivity without therapy ≥3 months duration|
+|:::|Chronic|Persistent with relapse <3 months after discontinuing therapy|
+===== Grading Vitreous Cells =====
+^ Grade          ^ Number of Vitreous cells  ^
+| 0              | No cells                  |
+| 0.5+ or trace  | 1-10                      |
+| 1+             | 11-20                     |
+| 2+             | 21-30                     |
+| 3+             | 31-100                    |
+| 4+             | >101                      |
+===== Grading Vitreous Flare =====
+^ Grade ^ Descriptors ^
+|0|No inflammation present|
+|0.5+|Trace inflammation present (slight blurring of optic nerve margins, normal striations and reflex of nerve fiber layer cannot be visualized)|
+|1+|Mild blurring of the optic nerve and retinal vessels|
+|2+|Optic nerve visible, borders blurred markedly|
+|3+|Optic nerve head not visible|
+|4+|  |
+===== Activity of Uveitis =====
+^ Term ^ Definition ^
+|Inactive|Grade 0 cells (in anterior chamber)|
+|Worsening activity|2-step increase in level of inflammation (i.e., anterior chamber cells, vitreous haze or increase from grade 3+ to 4+)|
+|Improved activity|2-step decrease in level of inflammation (i.e., anterior chamber cells, vitreous haze or decrease to grade 0)|
+|Remission|Inactive disease for ≥3 months after discontinuing all therapy for eye disease|
+===== Reference =====
+The Standardization of Uveitis Nomenclature (SUN) Working Group. [[http://www.ajo.com/article/S0002-9394(05)00407-1/fulltext|Am J Ophthalmol 2005;140:509-516]]
+ {{tag>jia uveitis}}

jia uveitis