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--- tubulointerstitial_nephritis_uveitis_syndrome_pediatric_patients [2025/02/09 02:46] – Scott Larson
+++ tubulointerstitial_nephritis_uveitis_syndrome_pediatric_patients [2025/02/09 03:17] (current) – removed Scott Larson
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-====== Tubulointerstitial Nephritis and Uveitis Syndrome (TINU) ======
-==== Diagnostic Criteria ====
-**Standardization of Uveitis Nomenclature Criteria 2021**
-==Clinical Criteria==
-  - Anterior uveitis with our without intermediate/posterior involvement
-    - Anterior chamber cell
-    - If vitritis, choroiditis or retinal vasculitis anterior chamber inflammation is also present
-  - Tubulointerstitial nephritis
-    - Biopsy proven -OR-
-    - Elevated urine β-2 microglobulin -AND-
-    - Abnormal urinalysis or elevated creatinine
-==Exclusion criteria==
-    * Positive Syphilis serology
-    * Evidence of Sarcoidosis
-      * bilateral hilar adenopathy -OR-
-      * tissue biopsy with non-caseating granulomata
-====Prevalence in Pediatric Populations====
-  * up to 32% in those with sudden onset bilateral anterior uveitis
-  * In those with biopsy proven tubulointerstitial nephritis, 46% had uveitis but 84% if they were screened at the outset, then 3 and 6 months later.
-    * [[https://www.aaojournal.org/article/S0161-6420(12)01261-4/fulltext|Saarela V et al Tubulointerstitial nephritis and uveitis syndrome in children: a prospective multicenter study. Ophthalmology. 2013;120(7):1476–1481.]]
-====Resources====
-  * {{::tubulointerstitial_nephritis_and_uveitis_syndrome_in_pediatric_patients_2023.pdf | Tubulointerstitial Nephritis and Uveitis Syndrome in Pediatric Patients. Janetos TM et al. Ocular Immunology and Inflammation. 2023;31(10):1955-1964}}
-  * {{::classification_criteria_for_tubulointerstitial_nephritis_with_uveitis_syndrome_2021.pdf |Standardization of Uveitis Nomenclature (SUN) Working Group. Classification Criteria for tubulointerstitial nephritis with uveitis syndrome. Am J Ophthalmol. 2021;228:225-261
-{{tag>uveitis}}