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torpedo_maculopathy [2025/07/14 00:20] – created Scott Larsontorpedo_maculopathy [2025/07/14 00:46] (current) – Scott Larson
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 ====== Torpedo Maculopathy ====== ====== Torpedo Maculopathy ======
  
-  * Single oval shaped lesions +====Characteristics==== 
-  * Located close to the fovea- usually temporal +  * Single oval shaped lesion of the RPE 
-  * Not associated with vision loss+  * Located close to the fovea 
 +    * usually temporal and unilateral 
 +    * leading edge points towards the fovea 
 +  * Causes a scotoma 
 +    * Not associated with other vision loss 
 +  * OCT 
 +    * cleft of missing RPE or thin abnormal RPE 
 +    * degeneration of photoreceptors and loss of outer segments 
 +  * Fundus autofluorescence 
 +    * dark in the area of the lesion 
 +    * no leakage 
 +  * Fluorescein angiogram 
 +    * hyper-fluorescence 
   * In isolation not associated with other disease   * In isolation not associated with other disease
-  * Can occur with other pigmented lesions typically seen in Familial Adenomatous Polyposis +  * Can occur with other pigmented lesions typically seen in Familial Adenomatous Polyposis
  
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-{{::torpedo_maculopathy.jpg|}} +{{::torpedo_maculopathy_variation.jpg|}} 
-From reference [1]+Figure 3 from reference [2] \\ 
 +Variations in lesion pigmentation in torpedo maculopathy. 
 +(A) Lesion in patient 6, entirely hypopigmented. This allows visualisation of the deeper choroidal vessels and the sclera. (B) In patient 7, there is variable degree of hypopigmentation and a temporal region of hyperpigmentation within the lesion. (C) In patient 9, the lesion consists of only mild hypopigmentation with a hyperpigmented area within it. (D) The hypopigmented lesion in patient 4 consists of a hyperpigmented temporal crescent. 
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 +{{::torpedo_maculopathy_montage.jpg|}} 
 +Figure 1 from reference [2] \\ 
 +Torpedo maculopathy in patient 1. (A) Hypopigmented lesion along the horizontal raphe with a tip towards the centre of the macula and a slightly pigmented tail. (B) Lesion hyperfluorescence on fluorescein angiography, secondary to the window defect. (C) Horizontal optical coherence tomography (OCT) (Stratus OCT; Carl Zeiss Meditec, Dublin, California) image taken of the superior aspect of the lesion revealing a large cleft and a seemingly absent retinal pigment epithelium signal. (D) Humphrey visual field (10-2) testing showing a corresponding scotoma. (E) Fundus autofluorescence shows hypoautofluorescence of the lesion. (F) Same OCT (Stratus OCT; Carl Zeiss Meditec, Dublin, California) cut of the lesion 2 years later showing no change in the cleft. There is increased irregularity in the photoreceptor layer of the retina. (G) Spectralis HRA+OCT (Heidelberg Engineering, Heidelberg, Germany) taken 4 years later showing the large cleft, the abnormal outer retinal layer, and the increased signal transmission in the choroid more clearly. (H) Three-dimensional view of the lesion using Spectralis OCT.
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