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tacrolimus [2025/01/20 02:15] Scott Larsontacrolimus [2025/06/14 04:24] (current) – [Resources] Scott Larson
Line 15: Line 15:
     * available for animals      * available for animals 
  
-===Black Box Warning===+=== Black Box Warning ===
  
-**Long-term Safety of Topical Calcineurin Inhibitors Has Not Been +<WRAP alert round 100%>  
-Established**+ 
 +Long-term Safety of Topical Calcineurin Inhibitors Has Not Been 
 +Established
  
 Although a causal relationship has not been established, rare cases of Although a causal relationship has not been established, rare cases of
Line 31: Line 33:
 PROTOPIC Ointment is not indicated for use in children less than 2 PROTOPIC Ointment is not indicated for use in children less than 2
 years of age. Only 0.03% PROTOPIC Ointment is indicated for use years of age. Only 0.03% PROTOPIC Ointment is indicated for use
-in children 2-15 years of age.+in children 2-15 years of age. 
  
 +</WRAP>
  
-==== Resources ==== 
-  * {{::tacrolimus_dermatologic_package_insert_fda.pdf|FDA package insert for Tacrolimus}} 
-  * {{::efficacy_of_topical_application_of_tacrolimus_eye_ointment_in_teh_managment_of_allergic_conjunctivitis_2015.pdf|Hazarika AK et al. Efficacy of topical application of 0.03% tacrolimus eye ointment in the management of allergic conjunctivitis. J Natural Science, Biology and Medicine 2015;6(1):S10-12}} 
-  * {{::effecs_of_tacrolimus_eye_drops_for_refractory_allergic_disease_2014.pdf|Fukushima A et al. Therapeutic effects of 0.1% tacrolimus eye drops for refractory allergic ocular diseases with proliferative lesion or corneal involvement. Br J Ophthalmology 2014;98-1023-1027}} 
-  * {{::long_term_outcome_of_tacrolimus_eye_drops_in_eyes_with_serere_allergic_conjunctival_diseases.pdf |Yazu H et al. Long-term outcomes of 0.1% tacrolimus eye drops in eyes with severe allergic conjunctival diseases. Allergy, Asthma &Clinical Immunology 2021;17(11)}} 
  
 +==== Resources ====
 +  * <wrap em>[[https://1drv.ms/b/c/31d83ae8e55e0542/EfUdSFGpXaVLoJmDHQ6K3fwBDNGgZC2B1JAau8u9LByjPw?e=zE88VD|FDA package insert for Tacrolimus]]</wrap>
 +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/ERPuYT3qeXBDlKCoNmMz4HYBbH0ZvORoGVjNZhVC09HrFQ?e=dh5VA6|Hazarika AK et al. Efficacy of topical application of 0.03% tacrolimus eye ointment in the management of allergic conjunctivitis. J Natural Science, Biology and Medicine 2015;6(1):S10-12]]
 +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EYz_NyvwrhZBkod4KFxRlYgB_5d68x49Y7IIh8Ke-JQx7g?e=OdikWJ|Fukushima A et al. Therapeutic effects of 0.1% tacrolimus eye drops for refractory allergic ocular diseases with proliferative lesion or corneal involvement. Br J Ophthalmology 2014;98-1023-1027]]
 +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EeN6CHndda5MpccDsZjWNgYBZn9OjgSn_Z8Jk6Nt0cMFEA?e=zu0XNE |Yazu H et al. Long-term outcomes of 0.1% tacrolimus eye drops in eyes with severe allergic conjunctival diseases. Allergy, Asthma &Clinical Immunology 2021;17(11)]]
  
 +{{tag>drugs}}