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sympathomimetic_eyedrops [2015/11/10 03:53] – external edit 127.0.0.1sympathomimetic_eyedrops [2025/04/18 20:40] (current) – external edit 127.0.0.1
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   * have more effects on CNS   * have more effects on CNS
     * Apraclonadine: weakly binds to Alpha-1 receptors     * Apraclonadine: weakly binds to Alpha-1 receptors
 +      * Will cause dilation in Horner syndrome pupil due to this binding effect and upregulation of the receptor that occurs 2-5 days after sympathetic block 
     * Bromonidine (Alphagan P) is similar with less Alpha-1 effect on pupil     * Bromonidine (Alphagan P) is similar with less Alpha-1 effect on pupil
  
 ==== Indirect Acting Agents ==== ==== Indirect Acting Agents ====
-  * Cocaine: blocks reuptake of norepinepherine+  * Cocaine: blocks reuptake of norepinephrine  
 +    * causes dilation in normal pupil but not in a Horner syndrome pupil
   * Amphetamine: causes release of and blocks reuptake of norepinepherine   * Amphetamine: causes release of and blocks reuptake of norepinepherine
 +    * causes dilation in normal pupil but not in a Horner syndrome pupil. 
  
 {{tag>drugs}} {{tag>drugs}}