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orkambi [2021/04/05 03:18] – created Scott Larsonorkambi [2025/04/18 20:40] (current) – external edit 127.0.0.1
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   * [[https://www-bmj-com.proxy.lib.uiowa.edu/content/361/bmj.k1783|Review Article]]   * [[https://www-bmj-com.proxy.lib.uiowa.edu/content/361/bmj.k1783|Review Article]]
  
-==== Cataracts with Ivacaftor ====+==== Cataracts with Lumacaftor/Ivacaftor ====
   * Cataracts were found in juvenile rats in pre-clinical toxicology studies   * Cataracts were found in juvenile rats in pre-clinical toxicology studies
   * Cataracts have been discovered in a few children taking this drug. The concomitant use of steroids or other pre-existing coniditions could not be excluded.    * Cataracts have been discovered in a few children taking this drug. The concomitant use of steroids or other pre-existing coniditions could not be excluded. 
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   * Drug manufacturer recommends baseline and follow-up eye examinations of unspecified interval or duration    * Drug manufacturer recommends baseline and follow-up eye examinations of unspecified interval or duration 
     * [[https://pi.vrtx.com/files/uspi_lumacaftor_ivacaftor.pdf|Prescribing Information]]     * [[https://pi.vrtx.com/files/uspi_lumacaftor_ivacaftor.pdf|Prescribing Information]]
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 +{{tag>drugs}}