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| optic_nerve_hypoplasia [2025/02/21 06:32] – Scott Larson | optic_nerve_hypoplasia [2025/06/14 03:21] (current) – [Resources] Scott Larson |
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| * Ratio of Mean Disc Diameter (DD) to Macula-Disc distance (DM) | * Ratio of Mean Disc Diameter (DD) to Macula-Disc distance (DM) |
| * (Horizontal + Vertical Disc Diameter /2) : Distance from center of disc to the center of the macula | * (Horizontal + Vertical Disc Diameter /2) : Distance from center of disc to the center of the macula |
| * {{::dd-dm_ratio.png?600|DD:DM ratio measurements}}\\ from Dutton GN. Congenital Disorders of the optic nerve: excavations and hypoplasia. Eye.2004;18:1038-1048 | * {{::dd-dm_ratio.jpg?600|DD:DM ratio measurements}}\\ from Dutton GN. Congenital Disorders of the optic nerve: excavations and hypoplasia. Eye.2004;18:1038-1048 |
| * OPTOS photographs of 188 adults and children with OHN (108) compared to normals (88) | * OPTOS photographs of 188 adults and children with OHN (108) compared to normals (88) |
| * Normal optic nerve horizontal diameter: 1.70 mm (95% CI 1.49, 2.14) | * Normal optic nerve horizontal diameter: 1.70 mm (95% CI 1.49, 2.14) |
| * Hypoplasia horizontal optic nerve diameter: 1.23 mm (95% CI 0.38, 1.45) | * Hypoplasia horizontal optic nerve diameter: 1.23 mm (95% CI 0.38, 1.45) |
| * {{::direct_optos_nerve_size_in_optic_nerve_hypoplasia_in_alaska_2020.pdf |Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499}} | * [[https://1drv.ms/b/c/31d83ae8e55e0542/ESt_2Vue-oRMuDq8pKqJrdEBpLHeUPKemCnXeNISNjZA0w?e=bKhGI1|Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499]] |
| * Optical Coherence Tomography | * Optical Coherence Tomography |
| * Suggestive of hypoplasia if the disc area is **<1.5 mm²** | * Hypoplasia may be present the disc area is **<1.3 mm²** |
| * Many commercial devices will attempt to plot the disc diameter and area | * Many commercial devices will attempt to plot the disc diameter and area |
| * [[optic_disc_area_calculator|Use this calculator to estimate the nerve area using the Heidelberg OCT machine optic nerve report without the glaucoma upgrade]] | * [[optic_disc_area_calculator|Optic Disc Area Calculator]] |
| * [[optic_disc_area|Normal values for optic discs measured by OCT]] | * [[optic_disc_area|Normal values for optic discs measured by OCT]] |
| * MRI | * MRI |
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| ======Resources====== | ======Resources====== |
| * {{::incidence_and_associated_endocrine_and_neurologic_abnormalities_of_optic_nerve_hypoplasia_2013.pdf |Mohoney BG et al. Incidence and Associated Endocrine and Neurologic Abnormalities of Optic Nerve Hypoplasia. JAMA Ophthalmol. 2013:131(7)898-902. }} | * [[https://1drv.ms/b/c/31d83ae8e55e0542/EXou7apq3NFOlZH04pdLPqQBpiYNlBt9S-WmVznFg1SnYQ?e=j3DcTE |Mohoney BG et al. Incidence and Associated Endocrine and Neurologic Abnormalities of Optic Nerve Hypoplasia. JAMA Ophthalmol. 2013:131(7)898-902. ]] |
| * {{:congentital_disorders_optic_nerve_excavations_copy.pdf|Dutton GN. Disorders of the optic nerve: excavations and hypoplasia.Eye 2004;18:1038-1048}} | * [[https://1drv.ms/b/c/31d83ae8e55e0542/EbALeTleMYRGqziAQkiDphgB1fZLJ4kUM1l4z6GoJm9oyQ?e=zTQe6k|Dutton GN. Disorders of the optic nerve: excavations and hypoplasia.Eye 2004;18:1038-1048]] |
| * {{::direct_optos_nerve_size_in_optic_nerve_hypoplasia_in_alaska_2020.pdf |Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499}} | * [[https://1drv.ms/b/c/31d83ae8e55e0542/ESt_2Vue-oRMuDq8pKqJrdEBpLHeUPKemCnXeNISNjZA0w?e=A619Fu |Arnold AW et al. Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska. Clinical Ophthalmology 2020;14:491-499]] |
| * {{::comparison_of_heidelberg_retina_tomograph_with_disc-macula_distance_to_disc_2016.pdf |Pang Y. et al. Comparison of Heidelberg Retina Tomograph with disc macula distance to disc diameter ratio in diagnosing optic nerve hypoplasia}} | * [[https://1drv.ms/b/c/31d83ae8e55e0542/EQXHTUG146BNjm-6aMvfF_4BCx_ZOyFj_AXFPbXxYowuuw?e=o5KXUa |Pang Y. et al. Comparison of Heidelberg Retina Tomograph with disc macula distance to disc diameter ratio in diagnosing optic nerve hypoplasia]] |
| * {{::clinical_and_morphologic_spectrum_of_optic_nerve_hypoplasia_1999.pdf |Hellström A. et al. The Clinical and Morphologic Spectrum of Optic Nerve Hypoplasia. JAAPOS 1999;3(4):212-20}} | * [[https://1drv.ms/b/c/31d83ae8e55e0542/EUP2UMLDXHRDk-qp6d_7bF8BHBrRvLUVy8jVVt2ljf9tLw?e=UDqUYw |Hellström A. et al. The Clinical and Morphologic Spectrum of Optic Nerve Hypoplasia. JAAPOS 1999;3(4):212-20]] |
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| {{tag>optic_disc}} | {{tag>optic_disc}} |