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intravitreal_injection_retinoblastoma [2020/08/27 00:09] – [Tools] Scott Larsonintravitreal_injection_retinoblastoma [2025/06/14 03:33] (current) – [Tools] Scott Larson
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 ===== Tools ===== ===== Tools =====
-  * 1 ml syringe or smaller for drug delivery{{:1ml_syringe.png?200|}}+  * 1 ml syringe or smaller for drug delivery{{:1ml_syringe.jpg?200|}}
   * 30-33 gauge needle for drug delivery   * 30-33 gauge needle for drug delivery
   * EUA set up (lid speculum, indenter, indirect, condensing lenses, etc.)    * EUA set up (lid speculum, indenter, indirect, condensing lenses, etc.) 
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 ===== Steps ===== ===== Steps =====
 +  - Call Pharmacy (x64300) 20 minutes before desired drug delivery time. 
   - Choose an injection site distant from any vitreous or retinal tumors   - Choose an injection site distant from any vitreous or retinal tumors
   - Lower intraocular pressure to <10mmHg with digital massage   - Lower intraocular pressure to <10mmHg with digital massage
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   - [[pars_plana_sclerotomy|Inject 2.5-3 mm from limbus]] directing the needle towards the center of the vitreous but avoid known vitreous seeds   - [[pars_plana_sclerotomy|Inject 2.5-3 mm from limbus]] directing the needle towards the center of the vitreous but avoid known vitreous seeds
   - Before retracting the needle tip from the vitreous apply cryo to the injection site and the needle.    - Before retracting the needle tip from the vitreous apply cryo to the injection site and the needle. 
-  - Retract the needle and bathe the fornix with sterile water for 3 minutes+  - [[https://openophthalmologyjournal.com/VOLUME/8/PAGE/7/|Retract the needle and bathe the fornix with sterile water for 3 minutes]] 
   - Apply a drop of betadine   - Apply a drop of betadine
   - Inspect vitreous and retina if desired     - Inspect vitreous and retina if desired  
  
-{{:measuring_limbus.png?400|}} +{{:measuring_limbus.jpg?400|}} 
-{{:cryo_the_needle.png?400|}}\\+{{:cryo_the_needle.jpg?400|}}\\
 Source: The role of intravitreal chemotherapy for retinoblastoma. Manjandavida FP, Shields CL. Indian J Ophthalmology 2014;63(2):143 Source: The role of intravitreal chemotherapy for retinoblastoma. Manjandavida FP, Shields CL. Indian J Ophthalmology 2014;63(2):143
  
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 ===== References ===== ===== References =====
-  * {{ :intravitreal_chemotherapy_for_vitreous_disease_in_retinoblastoma_revisited-_from_prohibition_to_conditional_indications.pdf |Intravitreal chemotherapy for vitreous disease in retinoblastoma revisited: from prohibition to conditional indications. Munier et al. Br J Ophthalmology 2012;96:1078-1083}} +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EWlCL1uEXCVAmWX7f2YWwTABxFuYBf7aEdY0EHe5n3DyOA?e=EncjQ3 |Intravitreal chemotherapy for vitreous disease in retinoblastoma revisited: from prohibition to conditional indications. Munier et al. Br J Ophthalmology 2012;96:1078-1083]] 
-  * {{ :rb_intravitreal_treatment_efficacy_and_toxicity_2017.pdf |Efficacy and Toxicity of Intravitreous Chemotherapy for Retinoblastoma: Four-Year Experience. Francis et.al. Ophthalmology 2017;124:488-495}} +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/ERT3sFzwfM5DjU-ocX2bAU0Ba8kraq8d80tb1Ezyg1GLvw?e=MI5nCq |Efficacy and Toxicity of Intravitreous Chemotherapy for Retinoblastoma: Four-Year Experience. Francis et.al. Ophthalmology 2017;124:488-495]] 
-  * {{ :intravitreal_chemotherapy_in_retinoblastoma-_expanded_use_beyond_intravitreal_seeds.pdf |Intravitreal chemotherapy in retinoblastoma: expanded use beyond intravitreal seeds. Abramson et. al. Br J. Ophthalmol 2019;103:488-493}} +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EccUCyytVydAjes0LRlzSpUBmjrsstHWC99MKhCurhOZlQ?e=4ffhJt |Intravitreal chemotherapy in retinoblastoma: expanded use beyond intravitreal seeds. Abramson et. al. Br J. Ophthalmol 2019;103:488-493]] 
-  * {{ :the_role_of_intravitreal_chemotherapy_for_retinoblastoma.pdf |The role of intravitreal chemotherapy for retinoblastoma. Manjandavida FP, Shields CL. Indian J Ophthalmology 2014;63(2):141-145}}+  * [[https://1drv.ms/b/c/31d83ae8e55e0542/ESQQ4hAPEv1KkAEHQNA6y6cBOlomgVhyPNAAeYMgw6u9CA?e=i5tpun |The role of intravitreal chemotherapy for retinoblastoma. Manjandavida FP, Shields CL. Indian J Ophthalmology 2014;63(2):141-145]] 
 +  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EfmwgphbnFFEtx7o3DvtrmYB6BcDEYe3eHzXImxo9QB0uA?e=n7HcmS |Death by Water: Precautionary Water Submersion for Intravitreal Injection of Retinoblastoma Eyes. Francis et. al. Open Ophthalmology Journal 2014;8:7-11]]
  
  
-{{tag>procedure, drugs}}+{{tag>procedure, drugs, retinoblastoma}}