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horner_syndrome_and_cocaine [2016/05/17 23:31] Scott Larsonhorner_syndrome_and_cocaine [2025/04/18 20:40] (current) – external edit 127.0.0.1
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 +====== Horner syndrome and Cocaine ======
  
 +====Action of Cocaine====
 +Cocaine blocks reuptake of norepinepherine that is normally released from nerve endings.
 +In a sympathetic lesion, norepinepherine is not released.
 +
 +====Effects of Cocaine on Horner's pupil====
 +little or no effect
 +====Effects of Cocaine on Normal pupil====
 +dilation
 +====Test procedure====
 +  * Place not more than 2 drops of cocaine hydrochloride 10% in both eyes (2% for infants and children,4% and 5% can also work for adults)
 +  * Measure anisocoria 50-60 minutes later
 +  * 0.8 mm or greater anisocoria after the cocaine is highly suggestive of Horner syndrome
 +====False Positive result====
 +pupil held by membrane, scar or aberrant innervation//
 +[[cocaine_and_amphetamine_in_horner_syndrome|Image]]
 +{{tag>syndrome drugs}}