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--- hemangioma_treatment [2020/06/04 21:51] – [Dosing] Scott Larson
+++ hemangioma_treatment [2025/04/18 20:40] (current) – external edit 127.0.0.1
@@ Line 48: / Line 48: @@
     * if PHACE is suspected: MRI/ MRA of head and neck and Echocardiogram
     * Slow titration up, lowest effective dosing, inpatient observation and TID dosing
-=== Outpatient Treatment Initiation Protocol ===
+=== Protocol ===
-  - Baseline BP and HR
+[[propranolol_for_hemangioma_protocol|See Outpatient Treatment of hemangioma with Propranolol Protocol]]
-  - Propranolol 0.5 mg/kg (1 mg/kg/day) PO BID
-  - Check BP and HR 1 and 2 hours after first dose
-  - IF not tolerated:  gradually increase to 0.5 mg/kg PO
-  - IF tolerated: Ensure minimum of 6 hours between doses, warning signs, feed regularly and hold dose if PO intake compromised,  Discharge to home
-  - In 3-7 days: Increase dose to 0.75 mg/kg PO BID (1.5 mg/kg/day)
-  - Check BP and HR 1 and 2 hours after new dose
-  - If not tolerated:  Keep at 1 mg/kg/day and assess efficacy
-  - If tolerated: discharge home
-  - In 3-7 days Increase dose to 1 mg/kg PO BID (2 mg/kg/day)
-  - Check BP and HR at 1 and 2 hours after new dose
 === Treatment Location ===
@@ Line 83: / Line 73: @@
 =====Other Treatments=====
+  * Surgical Excision
-  * Surgical Excision
 ===== References =====
+  * See [[propranolol_for_hemangioma_protocol|Protocol for Outpatient Propranolol for Infantile and Childhood Hemangioma]]
   * A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma 2015 {{:oral_propranolol_in_infantile_hemangioma_randomized_controlled_trial_nejm.pdf|PDF}}
   * Initiation and Use of Propranolol for Infantile Hemangioma: Report of a Consensus Conference 2013{{http://pediatrics.aappublications.org/content/131/1/128?sso=1&sso_redirect_count=1&nfstatus=401&nftoken=00000000-0000-0000-0000-000000000000&nfstatusdescription=ERROR%3a+No+local+token|Journal of Pediatrics}}

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