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fluorescein [2019/10/04 12:48] – created Scott Larsonfluorescein [2025/04/18 20:40] (current) – external edit 127.0.0.1
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-====== Fluorescein Injection for Ocular Angiography ======+====== Fluorescein for Ocular Angiography ======
  
 ===== Drug Preparations ===== ===== Drug Preparations =====
    * Fluorescite 10% for injection in single use 5ml vials (Alcon Inc)    * Fluorescite 10% for injection in single use 5ml vials (Alcon Inc)
      * [[https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021980s000lbl.pdf|FDA information]]      * [[https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021980s000lbl.pdf|FDA information]]
 +     * [[https://medlibrary.org/lib/rx/meds/fluorescite-1/|Package Insert]]
 +   * AK-Fluor 10% (Akorn)
 +     * 100 mg/ml in 5 ml single vials 
 +     * [[http://www.akorn.com/prod_detail.php?ndc=17478-253-10|Info from Company]]
 +     * [[http://www.akorn.com/documents/catalog/package_inserts/17478-253-10.pdf|Package Insert]]
 +   * AK-Fluor 25% (Akorn)
 +     * 250 mg/ml in 2 ml single vials 
 +     * [[http://www.akorn.com/prod_detail.php?ndc=17478-250-20|Info from Company]]
 +     * [[http://www.akorn.com/documents/catalog/package_inserts/17478-250-20.pdf|Package Insert]]
  
 ===== IV Dosing ===== ===== IV Dosing =====
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     * 500 mg (100 mg/ml) via IV     * 500 mg (100 mg/ml) via IV
   * Children   * Children
-    * 35 mg for each 10 lbs body weight (7.7 mg/kg)+    * 35 mg for each 10 lbs body weight (7.7 mg/kg) up to 500 mg max.
  
 ===== Oral Dosing ===== ===== Oral Dosing =====
   * 10 cc (two vials) of 10% solution in 8 ounces of orange or apple juice    * 10 cc (two vials) of 10% solution in 8 ounces of orange or apple juice 
-    * [[https://cdn.ymaws.com/www.opsweb.org/resource/resmgr/boc_resourses_pdf/18-1-05.pdf|Journal of Ophthalmic Photography;Case Report by Jeffrey Sobel]]+    * [[https://cdn.ymaws.com/www.opsweb.org/resource/resmgr/boc_resourses_pdf/18-1-05.pdf|Jeffrey Sobel. Journal of Ophthalmic Photography. 1996:18(1):38-40]]
   * 25 mg/kg or 500 mg capsules    * 25 mg/kg or 500 mg capsules 
-    * [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1042172/pdf/brjopthal00582-0011.pdf|Oral Fluorescein Angiography using capsules]] +    * [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1042172/pdf/brjopthal00582-0011.pdf|Oral Fluorescein Angiography using capsules. British Journal of Ophthalmology 1990;74:458-461]] 
-    * +  * 4ml of 25% Fluorescein Lite (25mg/kg) (Hub Parmaceuticals) mixed with 30 ml Orange Juice, followed by additional 30 ml of plain orange juice to clear the taste. 
 +    * [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804067/pdf/nihms508676.pdf|Oral FFA vs SD-OCT. Retina. 2013 September;33(8):1574–1583]] 
    
 +{{tag>drugs}}