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episcleritis [2023/03/08 18:15] – created Scott Larsonepiscleritis [2025/04/18 20:40] (current) – external edit 127.0.0.1
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 ====== Episcleritis ====== ====== Episcleritis ======
-Self-limited inflammation of the episcleral layers (loose connective tissue layers with a vascular plexus between the conjunctiva and the sclera that are contiguous with Tenon's capsule) +  * Self-limited inflammation of the episcleral layers (loose connective tissue layers with a vascular plexus between the conjunctiva and the sclera that are contiguous with Tenon's capsule)  
 +  * Female Adults more common than Male adults and both more common than in children 
 +  * More common in boys than girls  
 +  * 50% may have a concurrent eye disease  
  
 ===== Associated Conditions ===== ===== Associated Conditions =====
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         * Toxoplasma         * Toxoplasma
         * Toxocara         * Toxocara
-    * Medications +  * Medications 
-      * Topiramate +    * Topiramate 
-      * Pamidronate+    * Pamidronate 
 + 
 +==== Work-Up ==== 
 +  * Consider if recurrent or other signs consistent with connective tissue disease (joint pain, fevers etc) vascular or dermatologic disease  
 +  * Possible testing: 
 +    * Rheumatoid factor (Rheumatoid Arthritis) 
 +    * Antinuclear antibody (collagen vascular disease) 
 +    * Serum uric acid (gout), 
 +    * Erythrocyte sedimentation rate (inflammation, vasculitis),  
 +    * Complete blood count with differential (infection, malignancy)  
 +    * VDRL/FTA-ABS (spirochete infection)  
 +    * Urinalysis  
 +    * PPD or Quantiferon Gold (mycobacteria) 
 +    * Chest x-ray (mycobacgteria) 
 +    * HLA-B27 (collagen vascular disease)