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cysticercosis [2026/05/26 18:30] – Scott Larsoncysticercosis [2026/05/26 18:35] (current) – Scott Larson
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     * Albendazole + cortiosteroids >90% resolution     * Albendazole + cortiosteroids >90% resolution
       * Standard regimen:        * Standard regimen: 
-        * albendazole PO (15mg/kg/day usually about 400 mg BID, max 1200 mg/day) for 10-14 days (FDA label permits up to 30 days)+        * albendazole PO (15mg/kg/day usually about 400 mg BID, max 1200 mg/day) for 10-14 days (FDA label permits up to 30 days but some evidence supports shorter courses 3-7 days for example)
         * prednisone PO (1mg/kg/day) given for the duration and the tapered.          * prednisone PO (1mg/kg/day) given for the duration and the tapered. 
       * possible persistent motility restriction, proptosis or ptosis       * possible persistent motility restriction, proptosis or ptosis
     * Treatment response monitored by vision exam, and repeat imaging.      * Treatment response monitored by vision exam, and repeat imaging. 
 +    * If cystic lesions persist beyond 6-12 months, retreatment is recommended. 
 +      * albendazole can be repeated, praziquantel can be added or switched to. 
 +      * a combination may be superior if ≥ 3 cysts 
 +    * Monitor: liver enzymes, CBC
 +      * Hepatotoxicity occurs in 16%
 +      * Leukopenia in 10%
 +      * Reversable alopecia may occur 
 +      * More common to have above with more prolonged treatment 
  
 ====References==== ====References====
   - [[https://1drv.ms/b/c/31d83ae8e55e0542/ESPvY4XqC1BPg1_kzYOcbUQBgRAIUlsb7_eISmJBNaZHLQ?e=ANUFCJ| Pujari A. et al. Cysticercosis in ophthalmology. Surv Ophthal. 2022;67:544-569]]   - [[https://1drv.ms/b/c/31d83ae8e55e0542/ESPvY4XqC1BPg1_kzYOcbUQBgRAIUlsb7_eISmJBNaZHLQ?e=ANUFCJ| Pujari A. et al. Cysticercosis in ophthalmology. Surv Ophthal. 2022;67:544-569]]
 +  - [[https://pubmed.ncbi.nlm.nih.gov/20060168/|Rath S. et al. Orbital cystercosis: clinical manifestations, diagnosis, management, and outcome. Ophthalmology 2010;117(3):600-605.]]