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behcets [2025/06/03 03:00] Scott Larsonbehcets [2025/06/03 03:12] (current) – [Ocular Findings] Scott Larson
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-====== Behçet'Disease ======+====== Behçet Disease ======
  
   * Systemic vascular inflammatory disorder affecting skin, mucous membranes, eyes, lungs, GI tract and CNS. It is characterized by:    * Systemic vascular inflammatory disorder affecting skin, mucous membranes, eyes, lungs, GI tract and CNS. It is characterized by: 
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     * Also puss filled bumps in the skin     * Also puss filled bumps in the skin
     * Arthritis     * Arthritis
 +  * Typically symptoms start in the 20's or 30's
 +====Ocular Findings====
     * Ocular Inflammation (66%)     * Ocular Inflammation (66%)
       * Conjunctivitis        * Conjunctivitis 
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         * Hypopion         * Hypopion
         * Panuveitis with vasculitis          * Panuveitis with vasculitis 
-        * Complications of uveitis+    * Complications of uveitis
           * cataracts, synechiae, band keratopathy           * cataracts, synechiae, band keratopathy
-    * Rare associations +====Other More Rare Findings==== 
-      inflammation of the brain or spinal cord +  Inflammation of the brain or spinal cord 
-      * blood clots, aneurism, GI vasculitis +  * blood clots, aneurism, GI vasculitis 
-    Typically symptoms start in the 20's or 30's+ 
 +====Etiology==== 
 +  Unknown autoimmune disorder 
 +  * Associated with the HLA-B51/B5 allele 
 +    * 57% of people with this genotype have Behçet syndrome
  
 ====Resources==== ====Resources====
 [[https://www-clinicalkey-com.slhs.idm.oclc.org/#!/content/clinical_overview/67-s2.0-0dc07703-d4fd-4a55-a3b1-e8d2954751c7|Clinical Key Monograph]] [[https://www-clinicalkey-com.slhs.idm.oclc.org/#!/content/clinical_overview/67-s2.0-0dc07703-d4fd-4a55-a3b1-e8d2954751c7|Clinical Key Monograph]]
 +
 +{{tag>syndrome uveitis}}